Hosts Luke Bryan and Peyton Manning will present the 56th Annual Country Music Association Awards, known as the CMA's, live from Nashville, Tennessee on ABC on Wednesday night. Here's what we know about the star-studded country music event:
Performers
The broadcast will kick off with an opening tribute to the late Loretta Lynn, who died last month at the age of 90. That tribute will feature performances from Miranda Lambert, Reba McEntire and Carrie Underwood.
Other performers slated to take the CMA stage include Kelly Clarkson, HARDY, Marcus King, Jimmie Allen, Kelsea Ballerini, Carly Pearce and the Zac Brown Band, according to the association's initial lineup announced in October.
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Also set to perform are Katy Perry and Thomas Rhett, Ashley McBryde with Brandy Clark, Caylee Hammack, Pillbox Patti and the Brothers Osborne.

Luke Bryan and Peyton Manning will present the 56th Annual Country Music Association Awards on Nov. 9. Lainey Wilson, seen here in August, is nominated for six awards at Wednesday's CMA Awards.
Nominees
Lainey Wilson leads the pack with six nods this year, including album of the year, song of the year, female vocalist of the year, music video of the year, musical event of the year and new artist of the year.
Not far behind with five nominations apiece are McBryde, Pearce, Chris Stapleton and Shane McAnally.
Presenters
There's no shortage of celebrities set to take the stage to hand out the awards. They include: Jessica Chastain, Wynonna Judd, Michael Shannon, Rex Linn, Little Big Town, Lady A and Breland.
Where to watch
The CMA Awards will air on Wednesday, Nov. 9 on ABC at 8 p.m. ET/5 p.m. PT. The awards show will be available to stream on Hulu the following day.
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Photos: Scenes from the 2021 CMA Awards

Alan Jackson presents the award for entertainer of the year at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Dan Smyers, left, and Shay Mooney, of Dan + Shay, perform "I Should Probably Go To Bed" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Kane Brown and Chris Young perform at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Luke Bryan performs at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

HARDY, from left, and Dierks Bentley perform at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Luke Bryan performs at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Jimmie Allen performs "Freedom Was a Highway" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Jimmie Allen performs "Freedom Was a Highway" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Chris Stapleton, left, and Jennifer Hudson perform at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Keith Urban performs at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Thomas Rhett performs "Country Again" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Blake Shelton performs "Come Back as a Country Boy" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey) at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Luke Combs performs "Doin' This" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Blake Shelton performs "Come Back as a Country Boy" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Miranda Lambert performs a medley at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Carrie Underwood performs "If I Didn't Love You" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Carly Pearce, left, and Ashley McBryde perform at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Gabby Barrett performs "The Good Ones" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Faith Fennidy, from left, Madeline Edwards, Mickey Guyton, and Brittney Spencer embrace after a performance at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

John Osborne, left, and T.J. Osborne, of Brothers Osborne, perform at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Carly Pearce accepts the female vocalist of the year award at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Chris Stapleton poses in the press room with the awards for entertainer of the year, male vocalist of the year, and album of the year at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Ed Rode)

Jennifer Hudson performs at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Luke Combs, left, accepts the award for entertainer of the year as presenter Alan Jackson looks on at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Jimmie Allen accepts the new artist of the year award at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Jason Aldean, left, and Carrie Underwood perform "If I Didn't Love You" at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Mark Humphrey)

Luke Combs poses in the press room with the award for entertainer of the year at the 55th annual CMA Awards on Wednesday, Nov. 10, 2021, at the Bridgestone Arena in Nashville, Tenn. (AP Photo/Ed Rode)